ANXA5 and androgen insensitivity syndrome: In a more recent study examining plasma endothelial EVs (CD105+, CD144+, and annexin V+) specifically carrying miRNA-155, a marked increase was observed both in the acute (<24 h) and subacute (24 h to 2 weeks) stages post AIS and was positively correlated to NIHSS score and infarct volume [94].