NEU1 and familial dilated cardiomyopathy: In a DCM mouse model induced by streptozotocin (STZ), cardiac NEU1 expression was increased and associated with the induction of cardiac inflammation, apoptosis and fibrosis by inhibition of 5’ AMP-activated protein kinase alpha (AMPKα) phosphorylation via liver kinase b 1 (LKB1), resulting in reduced SIRT3 and superoxid dismutase (SOD) 2 levels.