That notwithstanding, the present results suggest that rOn-CRP might mainly enhance inflammation at the early stages of S. agalactiae infection (6 h and 12 h post-infection) but inhibit inflammation in later hours (i.e., 24 h and 48 h) post-infection as evidenced by the increase in pro-inflammation factors IL-1β and TNF-α and anti-inflammation factors IL-10 and TGFβ, respectively. The gene discussed is IL1B; the disease is infection.