RAB8B and parasitic infectious disease: Nguni cattle are known to be tolerant to different endemic parasitic diseases [5], therefore the immunity-related genes within the candidate regions identified in Bartlow Combine and Kokstad populations (BOLA-N (Class IB MHC Antigen QA-2-Related), BOLA (Class IB MHC Antigen QA-2-Related), and Rab-8B) are potential targets of natural selection.