INS and hyperinsulinism: It should be noted that in this small sample of patients with coronary artery disease, the significant factors of oxidative stress in EAT adipocytes appeared to be not just manifest disorders of carbohydrate metabolism (diabetes mellitus type 2), but primarily the state of prediabetes, which encompassed latent disorders of glucose/insulin metabolism and was associated with postprandial hyperglycemia and hyperinsulinemia.