Chen et al. [45] compared the efficacy, safety, and immunogenicity of PF-05280014 with those of trastuzumab of EU origin (trastuzumab-EU) in combination with paclitaxel in a total of 702 patients with HER2+ BC (PF-05280014: 349 patients, trastuzumab-EU: 353 patients). Here, ERBB2 is linked to breast cancer.