Glioma-derived exosomes shuttle a lncRNA called lncRNA activated by TGF-β (lncRNA-ATB) to astrocytes that activate astrocytes through the suppression of miR-204-3p in an Ago-dependent manner, and activated astrocytes could, in turn, promote the migration and invasion of glioma cells [108]. This evidence concerns the gene TGFB1 and central nervous system cancer.