Furthermore, the lncRNA SNHG6 (small nucleolar RNA host gene 6) stabilized by its binding partner, NCBP3 (Nuclear cap-binding subunit 3), inhibits GBX2 (gastrulation brain homeobox 2) by mediating H3K27me3 modification induced by PRC2 (polycomb repressive complex 2) to facilitate the malignant progression in glioma [106]. The gene discussed is GBX2; the disease is central nervous system cancer.