In fact, DPP4 is expressed in the primary tissues involved in viral infection susceptibility, since it is highly expressed in the alveolar type 2 (AT2) cells of the distal lung, as well as on the surface of the epithelium, vascular endothelium, and fibroblasts of human bronchi, where it plays a role in different lung diseases [75]. This evidence concerns the gene DPP4 and lung disorder.