The process of EMT involves molecular reprogramming of the cells, including loss of cell adhesion molecules, such as E-cadherin, which changes the epithelial cell morphology, as well as overexpression of N-cadherin, osteopontin, Snail1, Snail2 (slug) and other interstitial proteins, thus, facilitating tumor cells to obtain higher potential with respect to migration, invasion, anti-apoptotic potential, and the degradation of extracellular matrix [4,44]. This evidence concerns the gene SNAI2 and neoplasm.