In particular, we envisage that more detailed investigations on experimental models of GBA1-, SYNJ1-, SYPH1-, TMEM230-, Parkin-, PINK1-, ATP13A2-, FBXO7- and SYT11-associated parkinsonism could provide new insight into the pathophysiological mechanisms leading to PD that may involve Rab dysfunction. The gene discussed is ATP13A2; the disease is Parkinsonism.