PTK2 and neoplasm: Focal adhesion kinase (FAK) is a non-receptor tyrosine kinase composed of multiple domains that regulate diverse cellular processes, including growth factor signaling, cell cycle progression, cell survival, cell motility, angiogenesis, and the establishment of an immunosuppressive tumor microenvironment (TME), through kinase-dependent and -independent scaffolding functions in both the cytoplasm and nucleus [5].