The direct influence of IL-17 on the inflamed KCs via their increased proliferative activity is enhanced due to its secretion from the majority of the diverse cell types implicated in the disease pathogenesis, with, nevertheless, the IL-23-dependent IL-17 secretion through the activation of Th17 being widely demonstrated as a core pathogenetic mechanism and utilized as a therapeutic approach [12]. The gene discussed is IL17A; the disease is dry eye syndrome.