HMGA2 and colorectal carcinoma: Moreover, YTHDC1 could bind to m6A-modified circNSUN2 to facilitate its export from the nucleus to the cytoplasm where cytoplasmic circNSUN2 formed an RNA-protein ternary complex with Insulin-Like Growth Factor 2 mRNA-Binding Protein 2 (IGF2BP2), high mobility group AT-hook 2 (HMGA2) mRNA and RNA-binding protein (RBP), resulting in the enhanced stability of HMGA2 which further promoted CRC liver metastasis [81].