The ability of AO to selectively accumulate in tumor lysosomes and, if activated, to induce LMP may be useful not only for the set-up of an in vitro lysosomal stability assay but also to treat cancer, since, depending on the rate of LMP, it can eventually culminate in uncontrolled necrosis or activation of apoptotic pathways [26]. This evidence concerns the gene PDLIM7 and cancer.