MMP8 and cancer: Moreover, MMP8 rs11225395 CT + TT was associated with reduced breast cancer relapse (p = 0.04), greater overall HR = 0.7, 95% CI 0.5–1.0, p = 0.02) and disease-free survival (HR = 0.7, 95% CI 0.5–0.9, p = 0.02) among women with stage 0–II cancer in the Shanghai Breast Cancer Study [28].