Although Gal-1, Gal-9, MMP7, COL9A1, and FASLG are overexpressed in different kinds of cancers, the analysis of their serum levels allows one to discriminate between healthy controls and woman affected by type I EC, and combining this analysis with a typical clinical manifestation of EC, such us bleeding and pelvic pain, might help early EC diagnosis, avoiding invasive diagnostic techniques. Here, COL9A1 is linked to cancer.