While, several studies reported abnormal elevations of circulating ANXA5 in familial hypercholesterolemia, hypertensive patients, and patients with myocardial infarction [30,31,32], levels of ANXA5 among the patients of current study were within normal range (0–2 ng/mL), similar to those reported in healthy population [24,33]. Here, ANXA5 is linked to familial hypercholesterolemia.