Antioxidative enzymes such as SOD, CAT, and GPX, and nonenzymatic antioxidant and antiinflammatory molecules such as vitamins A, C, D [92,180] and E, melatonin, resveratrol, GSH, NAC, silymarin, quercetin, curcumin, propolis, thymoquinone, Boswellia, and hesperidin, were suggested as the therapeutic agents against COVID-19 and some of them are being evaluated in clinical trials [181,182,183,184,185,186,187,188,189,190,191]. This evidence concerns the gene SOD1 and COVID-19.