In 2013, a strong susceptibility loci within the GTF2I–NCF1 intergenic region at 7q11.23 was identified for primary Sjögren’s syndrome (pSS), with the GTF2I rs117026326 as the most significant polymorphism (OR = 2.20, p = 1.31 × 10−53) [3]. The gene discussed is GTF2I; the disease is peeling skin syndrome.