In pulmonary inflammation induced by intratracheal (i.t.)lipopolysaccharide (LPS) in mice, pretreatment with EGCG given 1 h before LPS alleviated the lung injury, decreased total cell, neutrophil, and macrophage counts in the lung, reduced a lung edema, decreased activities of myeloperoxidase (MPO) and protein kinase Cα, and lowered levels of pro-inflammatory cytokines TNFα, IL-1β and IL-6 [39]. Here, MPO is linked to inflammation.