TNF and asthma: In another model of asthma induced by toluene diisocyanate-inhalation, administration of EGCG suppressed asthmatic reaction, decreased the number of inflammatory cells in BALF and their infiltration into the airways, decreased the expression of MMP-9 mRNA and protein in the lung tissue, and diminished ROS, TNFα, and IL-5 concentrations in BALF [186].