AKT1 and non-small cell lung carcinoma: NSCLC cells overexpress EGFR and c-Met, which recruit downstream signaling molecules such as extracellular signal-regulated kinase (ERK)1/2, MAPK, STAT3, protein kinase B (PI3K-Akt) or mammalian target of rapamycin (mTOR), enhancing cell growth and migration [211,212].