CDX2 and colorectal cancer: Additionally, curcumin supplementation significantly reduced N-cadherin, twist, snail and vimentin, and increased E-cadherin in colorectal cancer SW480 cells, indicating that curcumin could suppress the EMT process by suppressing caudal type homeobox 2 (CDX2)/Wnt family member 3a (Wnt3a)/β-catenin pathway [55].