Apart from the GABAergic neurons in the DG of the hippocampus, the Glutamatergic neurons are also closely related with depression and cognitive impairment [11], so we detected the immunofluorescence of VGluT1(the presynaptic gutamatergic transporter), a significant Glutamatergic neuron marker, in the DG of the hippocampus [36]. Here, SLC17A7 is linked to major depressive disorder.