This present study aims to examine the effects of PS on the developmental trajectories of the GABAergic system, i.e., the protein levels of KCC2, NKCC1, GABAA receptor α1/α5 subunits, PV, and pCREB, during adolescence in the PFC of male rat pups because of a greater tendency of anxiety-like behavior in males evoked by prenatal psychological stressors such as maternal restraint stress [28]. This evidence concerns the gene SLC12A2 and Anxiety.