No significant correlation was observed between a Ki-67 index ≥ 3% and sex (p = 0.499); FSH (p = 0.056), LH (p = 0.853), PRL (p = 0.345), GH (p = 0.716), TSH (p = 0.343), and ACTH (p = 0.516); Knosp grade (p = 0.670); tumor breaking through the sellar floor (p = 0.489); positive transcription factor (p = 0.383). This evidence concerns the gene POMC and neoplasm.