IGF2BP2 and Alzheimer disease: In addition, IGF2BP2 was highly expressed in the entorhinal cortex, hippocampus, posterior central gyrus, and superior frontal gyrus in AD patients and was significantly enriched in extracellular matrix receptor interaction, focal adhesion, cytokine–cytokine receptor interaction, and the TGF-β signaling pathway, which might be related to the occurrence of AD [60].