Based on this reasoning, the aim of the present study is to analyze the relationship of Klotho with proinflammatory cytokines (TNF-α, IL-6, and IL-8) and the lipid peroxidation products (Malondialdhyde = MDA) among alcoholics with or without liver cirrhosis, and its relationship with survival. Here, CXCL8 is linked to cirrhosis of liver.