AGT and triple-A syndrome: As AAA is a chronic inflammatory disease in which the aortic wall is expanded by the destruction of the vascular structure, the tissue of AAA is often accompanied by infiltration of monocytes and macrophages, differentiation and proliferation of smooth muscle, increased matrix metalloproteinases (MMPs) activity, and degradation of extracellular matrix, closely associated with AngII-induced oxidative stress and vascular inflammation [22,23].