AGT and triple-A syndrome: In AngII + saline mice, AngII infusion significantly increased aortic width and formed AAAs (mean width of the abdominal aorta: 1.72 ± 0.13 mm, Figure 1A); however, edaravone administration attenuated enlargement of aortic width and decreased AAA formation (mean width of the abdominal aorta: 1.31 ± 0.13 mm, p = 0.032 vs. AngII + saline group, Figure 1A).