In addition, digitoxin can inhibit the TNFα-dependent proinflammatory response to influenza virus infection [47], and has also been reported to be a potent and efficacious suppressor of TNFα-dependent proinflammatory cytokine expression in cystic fibrosis patients [300], and this antinflammatory activity may be significantly useful in COVID-19 patients. This evidence concerns the gene TNF and cystic fibrosis.