Four previously identified polymorphisms (MYBPC3:c.3288G>A, MYL2:c.132T>C, MYBPC3:c.2308+18C>G and CASQ2:c.1194T>C), associated with the occurrence of arrhythmias, were further used for survival analysis to assess the predisposition of the different genotypes to the occurrence of major and/or minor arrhythmic events in the follow-up [25]. The gene discussed is MYBPC3; the disease is cardiac arrhythmia.