For example, the three variants linked to multiple variables in the arrhythmia category (MYBPC3:c.3288G>A, MYBPC3:c.2308+18C>G and MYL2:c.132T>C) are in genes associated with hypertrophic cardiomyopathy (HCM), where arrhythmias are secondary to ventricular remodeling [50,51]. The gene discussed is MYBPC3; the disease is cardiac arrhythmia.