ATAD2 is often considered a critical transcription factor or coactivator among malignant tumor cells [13,82], regulating the transcriptional levels of related genes, which in turn promotes the proliferative and apoptotic activities of tumor cells through multiple signaling pathways, which require the combined action of the ATPase domain and the bromodomain [3,67,83]. Here, ATAD2 is linked to neoplasm.