Between 84 and 123 individual motor neurons exhibiting evidence of cytoplasmic disordered SOD1, pTDP-43 or p62 pathology were imaged in each of the three ALS subgroups, noting the presence of spatial overlap (colocalization) or segregation (coincidence) between pathologies where multiple were present within an imaged motor neuron. Here, SOD1 is linked to amyotrophic lateral sclerosis.