To test whether LNT combined with DLL1 overexpression can enhance the inhibitory effect on the growth of EO771 breast tumor, we orthotopically inoculated EO771 tumor cells with DLL1 overexpression (EO771-L1) or its control EO771-R1, then treated tumor-bearing mice with 1.0 mg/kg LNT every other day for 12 days (Fig. 1a). Here, DLL1 is linked to neoplasm.