Again, out of the 13 prioritized genes, 11 genes (CAT, RNASET2, CCR6, MTHFR, CBS, SOD3, SUOX, IKZF4, FGFR1OP, NOTCH4 and PMEL)showed interaction with at least one of the 194 genes implicated in vitiligo and documented in GeneMania, KEGG GENE Database and Harmonizome (Supplementary Fig. 2). The gene discussed is CAT; the disease is vitiligo.