ZFP36L1 and small cell lung carcinoma: Moreover, given the potent growth suppressive effects we observed after ZFP36L1 re-expression and its ability to promote an inflammatory-like state, it will be important to determine whether inhibition of other repressive epigenetic modifiers such as EZH2 and KDM5A that have been previously linked to the SCLC neuroendocrine phenotype, SCLC survival, and immunogenicity15,38,43–45 also restore ZFP36L1 expression and if so, whether their inhibition is additive/synergistic with LSD1 inhibition.