Compared with ASCL1-positive SCLC cell lines (Fig. 2d and Supplementary Fig. 5a–c), ZFP36L1 was either not induced or only weakly induced by ORY-1001 or CC-90011 in 3 NEUROD1-positive SCLC cell lines (Supplementary Fig. 5g–j), suggesting that de-repression of ZFP36L1 after LSD1 inhibitor treatment is more selective in ASCL1-positive SCLCs compared to NEUROD1-positive SCLCs. This evidence concerns the gene ASCL1 and small cell lung carcinoma.