When assessing the differences in specific tests, excluding the 128 patients with ALS-FTD, we found a significantly worse performance of ATXN2+ patients in the RAVL − Delayed Recall (p=0.023), the BSRT − Immediate Recall (p=0.044), and in the Executive Functions domain of ECAS (p=0.034) (online supplemental tables 3 and 4). Here, ATXN2 is linked to amyotrophic lateral sclerosis.