LRRK2 and Parkinson disease: Testing of XL01126 and cis-XL01126 on SH-SY5Y, a human neuroblastoma cell linewidely used as PD cell model,58 revealedthat XL01126 induced 50% or more degradation of LRRK2 after 6 h/300nM or 24 h/300 nM treatment (Figure S7).