ADORA2A and Alzheimer disease: The Total Score results indicated that many vital targets involved in AD or PD, for example AChE (ACHE), MAO-B (MAOB), GluN2B-NMDAR (GRIN2B), adenosine A2A receptor (A2AR, ADORA2A) and cannabinoid receptor 2 (CB2R, CNR2), have potent predicted binding activity with several SCT constituents.