Comparing the identified molecular events and AOs to the three AOPs, including (1) AOP72: epigenetic modification of PPARG leading to adipogenesis, (2) AOP149: peptide oxidation leading to hypertension, and (3) AOP226: SSRI (selective serotonin reuptake inhibitor) leading to hypertension, which are related to either obesity or hypertension, showed that some of our identified events matched well to citable AOPs (Figure 3). The gene discussed is PPARG; the disease is hypertensive disorder.