Most importantly, we identified zafirlukast, a synthetic antagonist of the cysteinyl leukotriene receptor 1 (CysLTR1) commonly used to treat asthma [18], which was able to differentiate SBGS into brown adipocytes to a similar extent to the positive control rosiglitazone (Figure 1d,e). Here, CYSLTR1 is linked to asthma.