PRL and hypothyroidism: NAFLD is associated with alterations in various endocrine tissues, namely thyroid (hypothyroidism and decreased ratio of Thyroxine (T4)/Triiodthyronine (T3)), ovaries (increased or decreased estrogen and increased androgen levels) and testis (decreased testosterone levels), pituitary gland (increased adrenocorticotropic hormone and prolactin and decreased growth hormone levels), adrenal glands (increased glucocorticoid, androgen levels and activation of the renin–angiotensin–aldosterone system) and pancreas (T2DM) [13].