For instance, the neighboring genes of CTSBa, including fanconi anemia complementation group M (fancm), set and mynd Domain Containing 2a (smyd2a), German-Chinese forum on computational catalysis 2 (gcfc2), transcription factor B2, mitochondrial (tfb2m), potassium channel tetramerization domain-containing 3 (kctd3), and estrogen-related receptor gamma (esrrg), were conserved among black rockfish, zebrafish, and channel catfish (Figure 4C). The gene discussed is ESRRG; the disease is anemia (phenotype).