In a study population of 806 subjects with type 2 diabetes (T2D) from the Tousand&2 Study including 141 (17.5%) patients with HFpEF, 646 controls without HF and 19 patients with HFrEF, authors evaluated the association between cardiovascular events and MR-proANP, during a median follow up of 4.8 years. The gene discussed is NR3C2; the disease is hydrops fetalis.