Actin filamentin-1 antisense RNA (AFAP-AS1), zinc finger E-box binding homeobox 1-antisense 1 (ZEB-1-AS1), and HOX transcript antisense intergenic RNA (HOTAIR) are correlated with poor prognosis of HCC, whereas reduced expressions of 18 lncRNAs, including growth arrest-specific transcript 5 (GAS5), XIST, and maternally expressed gene 3 (MEG3), are correlated with an even worse prognosis of HCC [28]. This evidence concerns the gene ZEB1 and hepatocellular carcinoma.