Among these molecules, IFN-γ can induce tumor cell cycle arrest and establish tumor cell dormancy [71], and IL-12 can promote Th1 antitumor immune response which may be secreted by the stimulation of IFN-γ and in turn triggers the re-activation of the IFN-γ production cycle [72], while IL-10 and IL-13 can inhibit Th1 cells from secreting IFN-γ [73]. Here, IFNG is linked to neoplasm.