SOST and prediabetes syndrome: When all the study participants were considered, circulating sclerostin showed a significant positive correlation with fasting blood sugar (r=0.200, p=0.009), HbA1c (r=0.394, p<0.001), PPBS (r=0.267, p<0.001) and FFA (r=0.205, p=0.007), However, almost all above-mentioned parameters lost significance when the three groups were taken into account separately, with the exception of the HbA1c level in the healthy control (r=0.438, p=0.001), prediabetes group (r=0.334, p=0.011), and in the newly diagnosed T2D group (r=0.258, p=0.05) (Figure 4).