Detection of tumor necrosis factor-alpha (TNF-α), interleukin- (IL-) 10, and VEGF in tumor of mice by ELISA showed that the expressions of TNF-α (P < 0.05) and VEGF in the miR-29b group were lower than those in the NC-A549 group, and the expression of IL-10 was higher than that in the NC-A549 group. Here, TNF is linked to neoplasm.