CYBB and atherosclerosis: For example, querying the two NADPH oxidase genes implicated in redox metabolism and atherosclerosis “CYBB” and “NOX4” (25, 26), in the Li et al. (13) dataset using the “GO_Biological_Process_2018” database shows the top function category as “superoxide anion generation,” and that (FB), macrophages (Mø), and smooth muscle cells (SMCs) highly express these genes (Figure 3).