AHR signaling pathway may modify metabolic pathways associated with amino acid, which inhibits the function of immune cells such as glioma-associated macrophages, T cells, antigen-presenting cells, astrocytes, and microglia, resulting in inhibitory changes in the immune microenvironment during the occurrence and development of gliomas, and promoting glioma invasion and migration (60, 62). Here, AHR is linked to glioma.