Cholesterol-rich LDL and other apolipoprotein B (ApoB)-containing lipoproteins, including very low-density lipoproteins (VLDL), intermediate density lipoproteins (IDL) and lipoprotein(a), m[Lp(a)], have a direct impact on the development of atherosclerosis and its cardiovascular consequences. Here, APOB is linked to atherosclerosis.