CXCL8 and acute respiratory distress syndrome: IL-8 predicts ARDS following major trauma (Donnelly et al., 1993; Folkesson et al., 1995) and is considered one of the most potent neutrophil chemo-attractants in inflammation (Hoffmann et al., 2002), and blocking IL-8 has been shown to protect rabbits from acid-aspiration-induced lung injury (Folkesson et al., 1995).